The study's lead author, UC Professor Randy Seeley, PhD, explained the theory behind the research in a Feb. 1 press release:
Peptides that target blood vessels in fat and cause them to go into programmed cell death (termed apoptosis) could become a model for future weight-loss therapies, say University of Cincinnati (UC) researchers. ...
"Think of fat tissue like a bathtub," [Prof. Seeley] says. "To keep the amount of water the same, you have to make sure that the speed of the water coming in and the water going out match. If the water is coming in faster than the water is going out, eventually you have to build a bigger bathtub.
"Obesity is the same. People who eat more calories than they burn have to build a bigger fat tissue 'bathtub,' and building new blood vessels is crucial to building this bigger bathtub. For each additional pound of fat tissue, you need to build a mile of blood vessels.
"What we found is that if we can target these fat tissue blood vessels, animals eat less and lose weight as their 'bathtubs' get smaller."
Labels: research, prevention
Posted By: Aspen/CRC
